中国组织工程研究Issue(44)：7667-7674,8.DOI:10.3969/j.issn.2095-4344.2013.44.002
适宜单层缝合置入的无支架猪主动脉瓣膜性能评价
Properties of stentless porcine aortic valve for single-layer suture and implantation
徐殊 1韩宏光 1王辉山1
作者信息
- 1. 解放军沈阳军区总医院心外科，辽宁省沈阳市 110001
- 折叠
摘要
Abstract
BACKGROUND:The artificial heart valve used in clinical application can be divided into stented and stentless. Stented valve is convenient for operations, with a low possibility of incompetency after transplantation. However stented valve cannot stimulate natural valve. OBJECTIVE:To reduce valve implantation time and improve valve properties, this study was designed to develop a new stentless porcine aortic valve for single-layer suture and implantation based on the design of valve in pig aortic root geometry optimization, and to further evaluate its performance by in vitro test. METHODS:(1) Stentless porcine aortic valve for single-layer suture was prepared. (2) The in vitro valve implantation experiment was performed with monolayer suture method. (3) The valve was detected by in vitro fluid mechanics test and fatigue test. RESULTS AND CONCLUSION:Stentless valve for single-layer suture has removed the valve hard, which contributes to reduce the damaged caused by blood flow on the valve leaflet, at the same time removal of the hard valve ring can widen the diameter of implanted valve and improve hemodynamics, even the implantation time of valve is shorter than traditional double-layer suture. The in vitro fluid mechanics test and fatigue test results are satisfactory. The future research lies in a complete elucidation of long operation time, postoperative long-term clinical efficacy and durability of stentless valve implantation.关键词
器官移植/心肺移植/主动脉瓣/生物瓣膜/心血管/无支架/植入方法/体外测试Key words
heart valve prosthesis implantation/stents/aortic valve/heart valves/thromboembolism/cardiac output分类
医药卫生引用本文复制引用
徐殊,韩宏光,王辉山..适宜单层缝合置入的无支架猪主动脉瓣膜性能评价[J].中国组织工程研究,2013,(44):7667-7674,8.
