中国组织工程研究Issue(44)：7771-7776,6.DOI:10.3969/j.issn.2095-4344.2013.44.019
正常兔胆道系统常规超声及超声造影表现
Conventional ultrasonography and contrast-enhanced ultrasonography of normal rabbit biliary ducts
摘要
Abstract
BACKGROUND:The experimental animal models can be used to in-depth investigate the effect of ultrasound and contrast-enhanced ultrasound in the diagnosis and treatment of ischemic biliary lesions. But there is no report on the phase timing standard of rabbit model contrast-enhanced ultrasound that used in various hepatobiliary diseases. OBJECTIVE:To investigate the ultrasonic appearance of normal rabbit biliary ducts with conventional ultrasonography and contrast-enhanced ultrasonography, and the criterion of contrast-enhanced ultrasonography phase timing of rabbit liver. METHODS:The conventional ultrasonography of hepatobiliary system was performed on 10 healthy New Zealand rabbits, and contrast-enhanced ultrasonography was performed on duct wal s that displayed in conventional ultrasonography, then the features were analyzed. RESULTS AND CONCLUSION:(1) The bile duct of normal New Zealand rabbits showed a portal to biliary caliber ratio of 3.59±0.54. (2) The detection rates of common and middle lobe bile ducts were significantly higher than that of lateral lobe bile ducts on both conventional ultrasonography and contrast-enhanced ultrasonography. (3) The phases of contrast-enhanced ultrasonography of normal rabbit liver were divided into arterial phase (10-20 seconds), portal phase (21-30 seconds) and late phase (31-180 seconds). The normal duct wal presented hyper-enhancing at arterial phase and persistent iso-enhancing at portal and late phases. The establishment of these parameters of normal New Zealand rabbits not only lays a foundation for the application of contrast-enhanced ultrasonography on biliary ischemia but also expands to other hepatobiliary models.关键词
器官移植/器官移植基础实验/胆道系统/超声/超声造影/动物模型/缺血型胆道病变/兔/肝脏/胆管/对比剂/国家自然科学基金Key words
organ transplantation/ultrasonography/biliary tract/ischemia/cholangiography分类
医药卫生引用本文复制引用
郑博文,任杰,郑荣琴,王平,曾婕,吕艳,周杰,张玉进,杨松林..正常兔胆道系统常规超声及超声造影表现[J].中国组织工程研究,2013,(44):7771-7776,6.基金项目
国家自然科学基金资助(30901465)；中央高校基本科研业务费专项资金资助；广东省大学生创新实验项目(201002267)@@@@National Natural Science Foundation of China, No.30901465 （30901465）
Special Funds for Fundamental Scientific Research of Central Universities （）
University Students Innovative Experimental Projects of Guangdong Province, No.201002267 （）
