中国组织工程研究Issue(47)：8275-8281,7.DOI:10.3969/j.issn.2095-4344.2013.47.021
经皮椎体成形中椎旁血管渗漏与骨水泥性肺栓塞
Relationship between paravertebral vascular leakage and pulmonary cement embolism during percutaneous vertebroplasty
王诗军 1邑晓东 1李淳德 1刘宪义 1卢海霖 1刘洪 1李宏 1于峥嵘 1孙浩林1
作者信息
- 1. 北京大学第一医院骨科，北京市 100034
- 折叠
摘要
Abstract
BACKGROUND:Percutaneous injection of bone cement into the vertebral body can enhance the vertebral strength and vertebral stability, and obtain pain relief. But the bone cement may leakage into the paravertebral vessels during injection, and may back to the right ventricle and flow into the pulmonary artery through vena cave and thus causing pulmonary embolism. <br> OBJECTIVE:To evaluate the relationship between cement paravertebral vascular leakage and pulmonary cement embolism during percutaneous vertebroplasty. <br> METHODS:Total y 134 cases of osteoporotic compression fractures treated with vertebroplasty were retrospectively analyzed. Among them, 23 cases of cement paravertebral vascular leakage were considered as the experimental group, and the 43 cases without cement paravertebral vascular leakage and had the complete imaging data were considered as the control group. The spine and chest X-ray films were taken before and after vertebroplasty to detect whether there were cement paravertebral vascular leakage and pulmonary cement embolism in the patients of two groups. <br> RESULTS AND CONCLUSION:Among the 134 patients, 23 patients had cement paravertebral vascular leakage, and accounted for 17.2%. Among the 23 patients with cement paravertebral vascular leakage, three cases had pulmonary cement embolism without chest symptoms, and accounted for 13%. No pulmonary cement embolism occurred in the 43 patients without paravertebral vascular leakage of the control group, and there was no significant difference between two groups (P=0.039). Although the patients with cement pulmonary embolism remained asymptomatic, pulmonary cement embolism remained possible if cement paravertebral vascular leakage was detected during vertebroplasty.关键词
生物材料/生物材料临床实践/骨水泥渗漏/肺栓塞/椎体成形术/骨质疏松性椎体压缩骨折/聚甲基丙烯酸甲酯/椎旁血管渗漏/并发症分类
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王诗军,邑晓东,李淳德,刘宪义,卢海霖,刘洪,李宏,于峥嵘,孙浩林..经皮椎体成形中椎旁血管渗漏与骨水泥性肺栓塞[J].中国组织工程研究,2013,(47):8275-8281,7.
