中国组织工程研究Issue(48)：8349-8354,6.DOI:10.3969/j.issn.2095-4344.2013.48.009
保护退变椎间盘的Topping-off技术
Topping-off technique for the protection of degenerative intervertebral disc
摘要
Abstract
BACKGROUND:Topping-off technique can be used for fixation treatment through the combination of fusion and interspinous dynamic device, in order to prevent or slow down the adjacent lumbar segment degeneration. <br> OBJECTIVE:To obverse the protective effect of Topping-off technique (posterior lumbar interbody fusion <br> procedure combined with the fixation of dynamic interspinous device Coflex) for the degenerative intervertebral disc. METHODS:A total of 32 patients with degenerative lumbar diseases who had been treated with Topping-off technique were included in this study. The Oswestry disability index, the Japanese Orthopaedic Association scores, range of motion for Coflex implanted segment and during the relative signal intensity of the Coflex implanted segment in MRI image were recorded and calculated preoperatively and the entire fol ow-up period. <br> RESULTS AND CONCLUSION:Al patients were fol owed-up for 20.6 months averagely. Up to the last fol ow-up, the Oswestry disability index and Japanese Orthopaedic Association scores were significantly improved when compared with those before treatment (P<0.001). There was no significant difference in the range of motion for Coflex implanted segment before and after treatment (P=0.19). The relative signal intensity of the Coflex implanted segment was significantly improved when compared with that before treatment (P<0.01). The clinical application of the Topping-off technique showed a protective effect on the intervertebral disc.关键词
骨关节植入物/脊柱植入物/腰椎/椎间融合术/非融合术/动态固定/内固定/相对信号强度/省级基金分类
医药卫生引用本文复制引用
赵成,徐建广,连小峰,李浩,邱满乐..保护退变椎间盘的Topping-off技术[J].中国组织工程研究,2013,(48):8349-8354,6.基金项目
上海市科委医学重点项目资助课题(09411953500)@@@@Key Project of Science and Technology Committee of Shanghai for Medicine, No.09411953500 （09411953500）
