中国组织工程研究Issue(51)：8863-8868,6.DOI:10.3969/j.issn.2095-4344.2013.51.013
纳米羟基磷灰石人工骨修复塌陷型胫骨平台骨折
Nano-hydroxyapatite artificial bone for collapsed fractures of the tibial plateau
摘要
Abstract
BACKGROUND:Nano-hydroxyapatite helps to improve the mechanical properties of bone implants. <br> OBJECTIVE:To study the clinical effect of nano-hydroxyapatite artificial bone on col apsed fracture of the tibial plateau. <br> METHODS:Fourteen cases of col apsed fracture of the tibial plateau combined with bone defects from March 2010 to September 2012 were analyzed retrospectively. The bone defect range was from 1.5 cm×1.0 cm to 3.1 cm×4.5 cm. Al patients were treated with nano-hydroxyapatite artificial bone at an implant amount of 5-14 g. Clinical and X-ray observations were applied at 1 week, 1 month and 3 months postoperatively. Hospital for Special Surgery scores were employed for recovery of knee function. <br> RESULTS AND CONCLUSION:The patients were fol owed up for 12-27 months. Except for one case of a smal amount of wound exudates, no general side effects occurred in 13 cases. X-ray photo showed an integrity interface between nano-hydroxyapatite artificial bone and host bone at 3 months after treatment. Primary healing was obtained in al cases without any complications. Hospital for Special Surgery score was increased to (88.7±4.3) points at 1 year later. These findings indicate that the nano-hydroxyapatite artificial bone has a good biocompatibility and biomechanics, and it may be an ideal artificial bone for repairing col apsed fractures of the tibial plateau.关键词
生物材料/纳米生物材料/纳米材料/羟基磷灰石/人工骨/胫骨平台骨折/塌陷型/省级基金分类
医药卫生引用本文复制引用
王大平,熊建义,朱伟民,黄江鸿,段莉,陈洁琳,张巨峰..纳米羟基磷灰石人工骨修复塌陷型胫骨平台骨折[J].中国组织工程研究,2013,(51):8863-8868,6.基金项目
深圳市科技研发项目(GJHZ20130412153906739, CXZZ20130321152713220),广东省医学科研基金项目(B2012320),广东省教育厅育才项目(2012LYM_0120)@@@@the Scientific Research and Development Program of Shenzhen City, No. GJHZ20130412153906739, CXZZ20130321152713220 （GJHZ20130412153906739, CXZZ20130321152713220）
the Medical Research Foundation of Guangdong Province, No. B2012320 （）
the Incubation Project of Guangdong Provincial Department of Education, No.2012LYM_0120 （）
