中国组织工程研究Issue(7)：1115-1120,6.DOI:10.3969/j.issn.2095-4344.2014.07.022
组织工程化牙齿再生：热点与应用
Tissue-engineered tooth regeneration:hotspots and clinical application
摘要
Abstract
BACKGROUND:Although several prosthetic methods, such as artificial denture and dental implants, are clinical therapies to tooth loss, they are thought to have safety and usage time issues. With the development of biological and biomaterial sciences, recently, tooth tissue engineering has attracted more and more attention. <br> OBJECTIVE:To reflect advances and problems of tissue engineering technologies for promotion of tooth regeneration. <br> METHODS:Using the keywords of“tissue engineering, tooth regeneration”in English and Chinese, PubMed and CNKI databases from 2007 to 2013 were retrieved. A total of 65 literatures addressing tooth regeneration and tissue engineering were col ected, including 25 Chinese articles and 40 English articles. Published early, repetitive, and similar researches were excluded. Final y, 48 articles were included. <br> RESULTS AND CONCLUSION:The combination of stem cells and suitable scaffolds is widely used in tooth regeneration today, and growth factors or bone marrow which can produce promote tooth regeneration are added as wel , which has achieved partial or whole tooth regeneration. But there are apparent deficiencies in studies which focus on mechanisms behind tooth regeneration.关键词
组织构建/组织工程/牙齿再生/生物材料/干细胞/浙江省自然科学基金Key words
tissue engineering/tooth loss/regeneration/stem cells分类
医药卫生引用本文复制引用
刘鹏鹏,沈慧娟,王子轶,吴银芳,金光勇,祁倩娴,曾宪智..组织工程化牙齿再生：热点与应用[J].中国组织工程研究,2014,(7):1115-1120,6.基金项目
浙江省自然科学基金项目(Y2110158)；嘉兴市科技计划项目(2011AY1053-1)；嘉兴市科技计划项目(2012AY1075-11)；浙江省大学生科技创新活动计划项目(2012R417006)；嘉兴学院重点SRT计划项目(851712004)@@@@the Natural Science Foundation of Zhejiang Province, No. Y2110158 （Y2110158）
the Science and Technology Program of Jiaxing City, No.2011AY1053-1,2012AY1075-11 （）
the Science and Technology Innovation Program of Undergraduate of Zhejiang Province, No.2012R417006 （）
Key Program of Student Research Training of Jiaxing University, No.851712004 （）
