中国组织工程研究Issue(8)：1161-1164,4.DOI:10.3969/j.issn.2095-4344.2014.08.003
双相钙磷生物陶瓷/硫酸钙骨水泥多孔三维支架的生物性能
Biological properties of biphasic tricalcium phosphate bioceramics/calcium sulfate bone cement porous three-dimensional scaffolds
谭迎赟 1白石 1廖运茂2
作者信息
- 1. 重庆医科大学附属口腔医院种植科，重庆市 400015
- 2. 口腔疾病研究国家重点实验室，四川省成都市 610041
- 折叠
摘要
Abstract
BACKGROUND:With the development of tissue engineering, porous bioceramics are more and more used to repair bone defects. Current research focuses on the biological synthesis of this bioceramics and its performance evaluation. <br> OBJECTIVE:To discuss the preparation of a new kind of bone cement and to determine its physicochemical properties and biocompatibility with osteoblasts. <br> METHODS:Biphasic tricalcium phosphate powders were prepared using co-precipitation method. The powder was turned into granular stuff by arabic gum. After sintering, porous hydroxyapatite/tricalcium phosphate bioceramics were harvested, and then mixed with alpha-hemihydrate to prepare the bone cement. <br> RESULTS AND CONCLUSION:X-ray diffraction confirmed that the synthetic substance was a kind of biphasic calcium phosphate ceramic having a porous structure. The bone cement could be in the plastic state within 3 minutes. The curing time was 15 minutes, and the curing temperature was 36.5℃. The maximum compression strength was 5.82 MPa, and the MTT toxicity was level 0. Osteoblasts could grew wel on the material surface.关键词
生物材料/骨生物材料/钙磷生物陶瓷/硫酸钙/骨水泥/理化性能/生物相容性Key words
biocompatible materials/calcium sulfate/hydroxyapatites/osteoblasts分类
医药卫生引用本文复制引用
谭迎赟,白石,廖运茂..双相钙磷生物陶瓷/硫酸钙骨水泥多孔三维支架的生物性能[J].中国组织工程研究,2014,(8):1161-1164,4.
