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急性肺血栓栓塞症临床特点分析--附185例报告

陈瑞滔 罗亮 曾勉

新医学Issue(1):25-29,5.
新医学Issue(1):25-29,5.DOI:10.3969/g.issn.0253-9802.2014.01.007

急性肺血栓栓塞症临床特点分析--附185例报告

Clinical features of acute pulmonary thromboembolism:a report of 185 cases

陈瑞滔 1罗亮 1曾勉1

作者信息

  • 1. 510080 广州,中山大学附属第一医院 MICU
  • 折叠

摘要

Abstract

Objective To explore the clinical characteristics of pulmonary thromboembolism(PTE).Method The clinical data of 1 85 PTE patients diagnosed by CT pulmonary angiography were collected,and their clinical characteristics,diagnosis and treatment were analyzed. Meanwhile,the patients were divided into two groups according to age,the older group (age >40 years,n=1 39 )and non-elderly group (age ≤ 40 years,n=46),and their clinical characteristics were compared. Result The most common risk factors were age (>40 years old,75.1%) and deep vein thromboembolism (45.9%) and acute infectious diseases (33.0%). Dyspnea was the main symptom in patients with PTE (68.1%),otherwise shortness of breath was the main sign in patients with PTE (35.1%). The arterial blood gas mostly showed hypocapnia and hypoxemia (36.6%),hypoxemia (33.8%). Patients whose D-dimer was more than 500 μg/L accounted for 70.9%.The main sign of chest X-ray was infiltration (49.6%). Sinus tachycardia (21.1%)was the most common abnormality in electrocardiogram. The main sign of echocardiography was Pulmonary hypertension (46.8%).1 35 cases received anticoagulation,35 cases received thrombolytic therapy,5 cases received implanting inferior vena cave filter tube therapy,one case received pulmonary embolectomy and 9 cases refused treatment. 1 64 ca-ses (88.7%)got improved,6 cases (3.2%)got progress and 6 cases (3.2%)died after treatment. The in-cidence of hypertension and diabetes in elderly group was significantly higher than those in non-elderly group.Meanwhile,the incidence of nephritic syndrome in non-elderly group was significantly higher than that in elder-ly group,P<0.01. Percentage of hemoptysis in the elderly group was significantly lower than that in non-eld-erly group,and percentage of patients without obvious signs were also higher than that in non-elderly group,P<0.05. Conclusion The main clinical characteristics of acute PTE patients were dyspnea,hypoxemia,high D-Dimer and pulmonary infiltrates,pulmonary hypertension. Most PTE patients received treatment can get im-provement. Patients who have risk factors of PTE and have dyspnea may suffer from PTE. Clinical manifesta-tions in patients of different ages may be different.

关键词

肺血栓栓塞症/诊断/治疗/预后

Key words

Pulmonary thromboembolism/Diagnosis/Treatment/Prognosis

引用本文复制引用

陈瑞滔,罗亮,曾勉..急性肺血栓栓塞症临床特点分析--附185例报告[J].新医学,2014,(1):25-29,5.

新医学

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0253-9802

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