新医学Issue(5)：342-344,3.DOI:10.3969/g.issn.0253-9802.2014.05.017
EB病毒感染与儿童原发性肾病综合征关系的研究
Relationship between epstein-barr virus and children primary nephrotic syndrome
摘要
Abstract
Objective To explore the relationship between epstein-barr virus (EBV)infection and children primary nephrotic syndrome. Methods Blood samples and renal biopsy tissue of 66 children with PNS were analyzed as PNS group,the EBV DNA、VCA antibodies (VCA-IgM、VCA-IgG),atypical lympho-cyte were detected.Samples of 68 children without kidney disease were enrolled as control group. The differ-ence between two groups about EBV DNA,VCA-IgM、VCA-IgG,atypical lymphocyte in blood were com-pared. EBV DNA、hemic-renal EBV DNA in renal tissue were also compared between simple type and nephrit-ic type of PNS. Results The positive rates of VCA-IgM and VCA-IgG in PNS group were higher than those of control group (P<0.05). And compared with simple type of PNS,the positive rates of VCA-IgMand VCA-IgG in nephritic type of PNS were significantly higher (P<0.05 ). The positive rate of hemic-renal EBV DNA expression in nephritic type of PNS was also higher than that of simple type of PNS (P<0.05 ). Conclusion There may be some relations between EBV and children PNS,especially nephritic type of PNS.关键词
EB病毒/原发性肾病综合征/儿童Key words
Epstein-barr virus/Primary nephrotic syndrome/Children引用本文复制引用
李素娥,唐骏,吴乐天..EB病毒感染与儿童原发性肾病综合征关系的研究[J].新医学,2014,(5):342-344,3.
