摘要
Abstract
Objective To evaluate the clinical efficacy of Qiliqiangxin capsule and safety on very elderly patients with chronic heart failure , and provide the basis for rational drug use .Methods 60 patients who were ≥80 year old with chronic heart failure were enrolled and randomly divided into control group and the treatment group , 30 cases in each group .2 groups were given diuretics , metoprolol succinate extended release tablets ( metoprolol ) or digoxin and other conventional western medicine, treatment group plus Qiliqiangxin capsule, 3 times a day.After 8 weeks of treatment, observed the clinical efficacy of serum brain natriuretic peptide ( BNP) and cardiac color Doppler echocardiography cardiac function index ( CI, LVEF, SV, CO) , and observed adverse reactions .Results In treatment group after treatment , the total effective rate was 93.33%(28/30), higher than control group of 73.34%(22/30), the difference was statistically significant ( P <0.05). BNP levels in the two groups after treatment were reduced than before treatment ( P <0.05), the treatment group compared with the control group, BNP levels decreased more significantly ( P <0.05).After treatment, HR, SV, CO, CI, LVEF val-ues of the two groups were improved than before treatment ( P <0.05), but no difference between the two groups was statisti-cally significant ( P >0.05).Both two groups found no serious adverse events .Conclusion Qiliqiangxin capsule clearly assisted treatment of chronic heart failure efficacy , safety, and can be used in very elderly patients with chronic heart failure .关键词
芪苈强心胶囊/高龄老年/心力衰竭,慢性/临床研究Key words
Qiliqiangxin capsule/Very elderly/Heart failure,chronic/Clinical research
