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连花清瘟胶囊辅治急性上呼吸道感染的疗效观察及其对 IFN-γ的影响

魏梅 宋煜勋 周红

疑难病杂志Issue(4):345-348,4.
疑难病杂志Issue(4):345-348,4.DOI:10.3969/j.issn.1671-6450.2014.04.005

连花清瘟胶囊辅治急性上呼吸道感染的疗效观察及其对 IFN-γ的影响

Effect of Lianhuaqingwen capsule on acute upper respiratory infection and their impact on the IFN- γ

魏梅 1宋煜勋 2周红1

作者信息

  • 1. 100073 首都医科大学电力教学医院/北京电力医院呼吸内科
  • 2. 100073 首都医科大学电力教学医院/北京电力医院健康管理中心
  • 折叠

摘要

Abstract

Objective To evaluate the efficacy and safety of Lianhuaqingwen capsule in the treatment of acute upper respiratory infection and observe the effect on interferon gamma ( IFN-γ) of patients .Methods 203 cases of acute upper re-spiratory tract infection were randomly divided into two groups , treatment group of 101 cases (oral Lianhuaqingwen capsules), 102 cases in the control group given azithromycin tablets .To compare the efficacy of two groups , while the two groups were each randomly selected 20 cases of venous blood before and after each treatment , the application of ELISA kits to detect the concentration of serum IFN-γ.Results Overall efficacy in the treatment group effectiveness , efficiency and the temperature drops various clinical symptoms and signs of improvement rates were higher , two groups of patients in the prevalence of serum IFNγlevels were significantly higher , decreased significantly after treatment , with the treatment group decreased more signifi-cantly ( P <0.05).After treatment, two group patients'WBC and neutrophil percentage were significantly decreased ( P <0.05), but between the two groups , the difference was not statistically significant ( P >0.05).The incidence of adverse re-actions was not significant difference ( P >0.05 ) .Conclusion Lianhuaqingwen capsule can relieve a variety of clinical symptoms of acute upper respiratory tract infection , and have some anti-inflammatory antiviral activity .

关键词

连花清瘟胶囊/上呼吸道感染,急性/IFN-γ

Key words

Lianhuaqingwen capsule/Upper respiratory tract infection , acute/IFN-γ

引用本文复制引用

魏梅,宋煜勋,周红..连花清瘟胶囊辅治急性上呼吸道感染的疗效观察及其对 IFN-γ的影响[J].疑难病杂志,2014,(4):345-348,4.

疑难病杂志

OACSTPCD

1671-6450

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