摘要
Abstract
Objective To test the optimum concentration of ropivacaine when combined with fentanyl in parturients undergoing labor during epidural analgesia. Methods 160 parturients undergoing labor selected for delivery with epidural analgesia were randomized into four groups: Group A (0.15% ropivacaine plus fentanyl 2 μg/mL) , Group B (0.175%ropivacaine plus fentanyl 2 μg/mL), Group C (0.2%ropivacaine plus fentanyl 2 μg/mL) and Group D (0.225%ropivacaine plus fentanyl 2 μg/mL). 40 cases as control group which were given the same treatments as that in the experimental group except painless labor. The labor pain, duration, delivery mode, visual analog scale (VAS) scores, Apgar scores, postpartum hemorrhage and maternal side-ef ects were recorded. Results Al intervention groups provided good analgesia, but group A with higher pain scores than group B, C and D. While labor duration was the same for every group in the second and third stages of labor, the intervention group experienced a relatively shorter first stage active phase and group A, B and C shorter than group D. Cesarean section rate in intervention groups were significantly lower than that in the control group (P<0.05),but there was no significant dif erence among every intervention group (P>0.05). Every group had no signi?cant dif erences with respect to rate of cesarean delivery, Apgar scores, hemorrhage of delivery, and maternal side-ef ects (P> 0.05). Conclusions 0.175 %-0.2% ropivacaine combined with fentanyl 2μg/mL epidural labor analgesia achieved the best results, had no adverse ef ect on maternal and infant, and it should be generalized in clinic.关键词
分娩镇痛/罗哌卡因/芬太尼/剖宫产率Key words
Labor analgesia/Ropivacaine/Fentanyl/Cesarean section rate
