摘要
Abstract
Objective To observe the immune function changes of HFMD and immunomodulatory ef ects of Astragalus injection combined with interferon. Methods fifty-eight cases of HFMD children in nervous system involvement stage were divided into 2 groups (28 cases in control group and 30 cases in Astragalus combined with interferon treatment group).Two groups were given basic treatment, and the treatment group were treated with Astragalus injection and interferon alfa-2b injection.To observer the general conditions and changes of cellular and humoral immune function in children,and evaluate the therapeutic ef ect of Astragalus injection and interferon. Results The dif erence was statistical y significant between the two groups in nervous system symptoms releif time and the process of heat and treatment (P< 0.05); at the 3 day of treatment, the CD3, CD4, IgM in control group had significant dif erence compared with those before treatment (P<0.05). Compared with control group and before treatment,al index of immune function in treatment group had significant dif erence (P< 0.05,). Conclusion Astragalus injection combined with interferon is ef ective in the treatment of hand foot and mouth disease.The mechanism. associated with immune regulation.关键词
手足口病/神经系统受累期/体液免疫/细胞免疫/黄芪注射液/干扰素Key words
Hand foot and mouth desease/Nervous system involvement stage/cellular immunity/Humoral immunity/Astragalus injection/Interferon分类
医药卫生
