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奥沙利铂联合5-Fu 3w方案治疗晚期胃癌疗效观察

朱西平 张振华 胡舰

医学信息Issue(26):124-125,2.
医学信息Issue(26):124-125,2.

奥沙利铂联合5-Fu 3w方案治疗晚期胃癌疗效观察

Observation on Effect of Tri-weekly Oxaliplatin Combined 5-Fu for the Treatment of Advanced Gastric Carcinoma

朱西平 1张振华 1胡舰1

作者信息

  • 1. 宁国市人民医院肿瘤科,安徽 宁国 242300
  • 折叠

摘要

Abstract

Objective:to observe the recent ef ect and toxicity of the combination of oxaliplatin and 5-Fu in treatment of patients with advanced gastriccaicinoma. Methods: 40 patinets with advanced gastric cancer were treated with 5-Fu plus oxaliplatin (110mg/m2, d1). 5-Fu was given 500mg/m2 (iv.bolus) and 800mg/m2 (24h continuous iv with pump) d1,d2, 21 days for a cycle. The ef icacy was evaluated by CT scan after 2 cycles. Results:the total ef ective rate was 47.5%(19/40),the main side ef ects were marrow inhibition, gastrointestinal reaction, Phlebitis and nervous system toxicity. Conclusion:tri-weekly oxaliplatin combined 5-Fu for the treatment of advanced gastric carcinoma is highly ef ective. It has less adverse reactions and can be wel tolerated in patients.

关键词

奥沙利铂/5-Fu/化学治疗/晚期胃癌

Key words

Oxaliplatin/5-Fu/Chemotherapy/Advanced gastric carcinoma

分类

医药卫生

引用本文复制引用

朱西平,张振华,胡舰..奥沙利铂联合5-Fu 3w方案治疗晚期胃癌疗效观察[J].医学信息,2013,(26):124-125,2.

医学信息

1006-1959

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