医学信息Issue(26):124-125,2.
奥沙利铂联合5-Fu 3w方案治疗晚期胃癌疗效观察
Observation on Effect of Tri-weekly Oxaliplatin Combined 5-Fu for the Treatment of Advanced Gastric Carcinoma
朱西平 1张振华 1胡舰1
作者信息
- 1. 宁国市人民医院肿瘤科,安徽 宁国 242300
- 折叠
摘要
Abstract
Objective:to observe the recent ef ect and toxicity of the combination of oxaliplatin and 5-Fu in treatment of patients with advanced gastriccaicinoma. Methods: 40 patinets with advanced gastric cancer were treated with 5-Fu plus oxaliplatin (110mg/m2, d1). 5-Fu was given 500mg/m2 (iv.bolus) and 800mg/m2 (24h continuous iv with pump) d1,d2, 21 days for a cycle. The ef icacy was evaluated by CT scan after 2 cycles. Results:the total ef ective rate was 47.5%(19/40),the main side ef ects were marrow inhibition, gastrointestinal reaction, Phlebitis and nervous system toxicity. Conclusion:tri-weekly oxaliplatin combined 5-Fu for the treatment of advanced gastric carcinoma is highly ef ective. It has less adverse reactions and can be wel tolerated in patients.关键词
奥沙利铂/5-Fu/化学治疗/晚期胃癌Key words
Oxaliplatin/5-Fu/Chemotherapy/Advanced gastric carcinoma分类
医药卫生引用本文复制引用
朱西平,张振华,胡舰..奥沙利铂联合5-Fu 3w方案治疗晚期胃癌疗效观察[J].医学信息,2013,(26):124-125,2.