摘要
Abstract
Objective To investigate the clinical,radiographic and pathologic features of Wegener granulomatosis (WG)for the sake of bet er understanding of this diseases. Methods By reporting a case of restrictive Wegener granulomatosis of lung and analyzing its clinicopathologic features in HE sections and special stains.We also reviewed associated documents. Results a mid-age woman who shows moderate pain in back and chest,with breathless,fatigue after exertion.CT demonstrated that multiple masses and nodular high density area with cavitation in both lungs. There are no abnormal changes in other organs. Histological y,irregular necrosis or aggregated neutrophils which like microabscess can be seen in central area of granuloma, vasolititis is another evident of this disease. Special stains: acid-fast stain and silver stain were both negative, elastic fiber stain is positive in most area. Conclusion restrictive WG is confined in lung,its basic alteration are necrotizing granulomas,microabscess and vasolitis, which shows apparent response to cortical steroids combined with cyclophosphamide.关键词
肺肉芽肿/局限型韦格纳肉芽肿/临床病理/特殊染色Key words
Pulmonary granulomatosis/Restrictive Wegener granulomatosis/Clinicopathology/Special stain
