中国康复理论与实践Issue(10):956-959,4.DOI:10.3969/j.issn.1006-9771.2013.10.015
A型肉毒毒素对脑性瘫痪患儿髂腰肌痉挛的疗效观察
Effect of Botulinum Toxin-A on Spastic Iliopsoas in Children with Cerebral Palsy
刘建军 1纪树荣 1吴卫红 1张雁 1曾凡勇 1李南玲1
作者信息
- 1. 首都医科大学康复医学院,中国康复研究中心,北京市100068
- 折叠
摘要
Abstract
Objective To observe the effect of Botulinum toxin-A (BTX-A) injection on spastic iliopsoas in the children with cerebral palsy. Methods July 2006 to August 2012, 37 cerebral palsy children with spastic iliopsoas were treated. The age ranged from 3 to 15 years. The control group (n=20) was treated by physical therapy. The experimental group (n=17) accepted BTX-A injection in addition. The dose of BTX-A block was identified with the weight of the child and the modified Ashworth Scale (MAS). The dose of injection ranged from 15 IU to 45 IU, average (31.2±13.9) IU. Results There was no significant difference between 2 groups in age, weight, MAS score, Gross Motor Function Measure (GMFM) score and extension angle of hip joints before treatment (P>0.05). In both groups, the MAS score decreased, GMFM score and extension angle of hip joints increased after 8 weeks. In the control group, the GMFM score improved significantly (P<0.05). In the experimental group, MAS score, GMFM score and extension angle of hip joints changed significantly after treatment. There was significant difference between 2 groups in MAS score, GMFM score and extension angle of hip joints after treatment (P<0.05). Conclu-sion The BTX-A injection can relieve iliopsoas spasticity on the children with cerebral palsy efficiently.关键词
脑性瘫痪/痉挛/A型肉毒毒素/髂腰肌/步态/粗大运动功能Key words
cerebral palsy/spasticity/Botulinum toxin-A/iliopsoas/gait/gross motor function分类
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刘建军,纪树荣,吴卫红,张雁,曾凡勇,李南玲..A型肉毒毒素对脑性瘫痪患儿髂腰肌痉挛的疗效观察[J].中国康复理论与实践,2013,(10):956-959,4.