中国康复理论与实践Issue(3)：259-261,3.DOI:10.3969/j.issn.1006-9771.2014.03.016
β-七叶皂苷钠对重型脑损伤患者血清肿瘤坏死因子-α的影响
Effect of β-aescine Sodium on Tumor Necrosis Factorα in Severe Traumatic Brain Injury
摘要
Abstract
Objective To study the effect ofβ-aescine sodium on tumor necrosis factorα(TNF-α) in patient with severe traumatic brain injury and the clinical significance. Methods 60 patients with severe traumatic brain injury were divided equally into control group (n=30) and treatment group (n=30), who accepted routine therapy and furtherβ-aescine sodium respectively. The serum TNF-αwas determined before and 1 d, 2 d, 3 d, 5 d and 7 d after treatment. The patients were assessed with Glasgow Outcome Scale (GOS) 3 months after treat-ment. Results There was significant difference of serum TNF-αbetween treatment group and control group since 3 d after treatment (P<0.05). The score of GOS was better in the treatment group than in the control group 3 months after treatment (P<0.05). Conclusionβ-aes-cine sodium is effective on severe traumatic brain injury. Level of TNF-αmay be related with the outcome of patients with severe traumatic brain injury.关键词
β-七叶皂苷钠/重型颅脑损伤/肿瘤坏死因子-αKey words
β-aescine sodium/severe traumatic brain injury/tumor necrosis factorα分类
医药卫生引用本文复制引用
邓元央,黄海能,韦桂源,黄华东,罗起胜,符黄德,李传玉..β-七叶皂苷钠对重型脑损伤患者血清肿瘤坏死因子-α的影响[J].中国康复理论与实践,2014,(3):259-261,3.基金项目
广西卫生厅科研立项课题(No.Z2010088)。 （No.Z2010088）
