中国全科医学Issue(10)：1129-1132,4.DOI:10.3969/j.issn.1007-9572.2014.10.012
颈动脉支架成形术对有症状及无症状性颈内动脉狭窄患者认知功能的影响研究
Influence of Carotid Artery Stenting on Cognitive Function in Patients with Asymptomatic and Symptomatic Internal Ca-rotid Stenosis
高连波 1李艳艳 1高红华 1李明1
作者信息
- 1. 110032辽宁省沈阳市，中国医科大学附属第四医院神经内科
- 折叠
摘要
Abstract
Objective To comparatively study the cognitive function in patients with asymptomatic and symptomatic in -ternal carotid stenosis before and after carotid artery stenting ( CAS) .Methods A total of 69 patients with severe unilateral in-ternal carotid artery stenosis (≥70%) were enrolled.Based on the severity of the stenosis and the degree of compensatory collat-eral flow, revealed by the whole brain angiography , patients were treated with CAS.Cognitive function was assessed 24 hours be-fore operation and 3 months after operation using the Mini -Mental State Examination ( MMSE) form and the Wechsler Adult In-telligence Scale-Revised for China ( WAIS-RC) .Results The CAS procedure was successful in all patients and no single case of postoperative complications was recorded.Prior to the operation , the MMSE score and the WAIS -RC score ( including immediate memory , working memory , attention and executive function ) results were all superior in asymptomatic patients as com-pared with symptomatic patients ( P<0.05 ) .At the follow-up visit 3 months after operation , all measurements were improved in both asymptomatic and symptomatic groups.However, the improvement was more pronounced in asymptomatic patients than in symptomatic patients.Conclusion Severe internal carotid artery stenosis impairs many aspects of cognitive function , particularly in symptomatic cases.Stenting can improve cognitive function , especially in asymptomatic patients.This suggests that asymptomat-ic patients with internal carotid artery stenosis have more rooms for improvement in cognitive function.关键词
颈内动脉狭窄/认知功能/颈动脉支架成形术Key words
Internal carotid stenosis/Cognitive function/Carotid artery stenting分类
医药卫生引用本文复制引用
高连波,李艳艳,高红华,李明..颈动脉支架成形术对有症状及无症状性颈内动脉狭窄患者认知功能的影响研究[J].中国全科医学,2014,(10):1129-1132,4.
