中国全科医学Issue(10)：1136-1139,4.DOI:10.3969/j.issn.1007-9572.2014.10.014
尿胰蛋白酶原-2诊断胰腺炎的医学决定水平探讨
The Explore on the Medical Decision Level of Urine Trypsinogen-2 Diagnosed Pancreatitis
摘要
Abstract
Objective To explore the medical decision level diagnosed pancreatitis of urinary trypsinogen -2, and e-valuate the reliability of the positive limit (50 μg/L) of trypsinogen-2 as a diagnosed medical decision level on the pancreatitis diagnosis, avoiding its misdiagnosis.Methods 175 cases of patients visiting our hospital from July , 2010 to August, 2011 and healthy people were chosen as the research objects.We collected the first diagnosis information of the patients , detected the con-centrations of urinary trypsinogen -2 and the concentrations of serum and urine amylase , and made a diagnosis of pancreases based on the results along with CT scan data and the clinical symptoms.We grouped the patients according to the first diagnosed disease type , and then we statistically analyzed differences of concentration of urinary trypsinogen -2 between disease group and healthy group and the misdiagnosis rate as pancreatitis in each group according to urinary trypsinogen -2 positive limit.Results The concentrations of urinary trypsinogen -2 in pancreatitis group was significantly lower than that in renal dysfunction group , but was significantly higher than that in healthy group ( P<0.05 ) , and was no statistical significance compared with digestive tract ulcer group and tumor group ( P>0.05 ) .Using the urinary trypsinogen -2 positive limit as diagnosis criteria for pancreatitis , the misdiagnosis rate in the Peptic ulcer group , tumor group, renal dysfunction group were 100.00%, 77.06%, 98.00%re-spectively.Conclusion It was fit to regard the positive limit of urinary trypsinogen -2 reported in the literature as medical deci-sion of awaiting diagnosis as pancreatitis , but not as the medical decision level making a definite diagnosis as pancreatitis .It was difficult to confirm the medical decision level diagnosing pancreatitis of urinary trypsinogen -2.The value of urinary trypsinogen -2 for diagnosing pancreatitis needed to be objectively evaluated by expanding the diseases species unrelated to pancreatitis for large sample investigation.关键词
尿胰蛋白酶原2/胰腺炎/医学决定水平Key words
Urinary trypsinogen-2/Pancreatitis/Medical decision level分类
医药卫生引用本文复制引用
刁奇志,董林玲,廖娟,李远..尿胰蛋白酶原-2诊断胰腺炎的医学决定水平探讨[J].中国全科医学,2014,(10):1136-1139,4.基金项目
重庆医科大学第五临床学院资助项目 （）
