中国动物传染病学报Issue(1)：80-86,7.
寄生虫乳酸脱氢酶研究进展
PROGRESS IN RESEARCH ON LACTATE DEHYDROGENASE OF PARASITES
摘要
Abstract
The survival of most parasites mainly depends on the glycolytic pathway, in which glucose is metabolized to lactic acid for their energy generation. Lactate dehydrogenase (LDH) as a terminal enzyme on anaerobic glycolytic pathway catalyzes the reversible reaction of pyruvate reduction to lactate and lactate oxidation to pyruvate. Thus LDH is closely associated with parasitic survival. Previous studies have showed that LDHs from different parasites exhibit particular physicochemical properties and molecular structures and play as ideal potential targets for diagnosis and drug screening. Research on LDH functions would provide useful information on searching potential antigen candidates for diagnostics and vaccine and on screening therapeutic drugs for parasitic diseases.关键词
乳酸脱氢酶/寄生虫/诊断/药物靶标/疫苗Key words
Lactate dehydrogenase/parasites/diagnosis/drug target/vaccine分类
农业科技引用本文复制引用
王艳歌,董辉,黄兵..寄生虫乳酸脱氢酶研究进展[J].中国动物传染病学报,2014,(1):80-86,7.基金项目
国家自然科学基金 （）
