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视网膜母细胞瘤化疗减容加局部治疗瘤体后的临床消退类型分析

田明星 周炼红 叶美红 罗琪 徐永红

中国斜视与小儿眼科杂志Issue(2):5-8,49,5.
中国斜视与小儿眼科杂志Issue(2):5-8,49,5.

视网膜母细胞瘤化疗减容加局部治疗瘤体后的临床消退类型分析

Retinoblastoma regression patterns following chemoreduction and adjuvant therapy

田明星 1周炼红 1叶美红 1罗琪 1徐永红1

作者信息

  • 1. 430060武汉,武汉大学人民医院眼科
  • 折叠

摘要

Abstract

Objective To evaluate retinoblastoma regression patterns following chemoreduction and adjuvant therapy. Methods Retrospective case series. the regression patterns following chemoreduction and adjuvant therapy of 63 cases (93 eyes) of retinoblastoma patients were researched. Results Retinoblastoma regressions were type 0 (n=3),type 1 (n=19),type 2 (n=6),type 3 (n=35),and type4 (n=75). Tumors with an initial thickness of 3 mm or less regressed most often to type 4 (84.21%),those 3 to 8 mm regressed to type 3(34.43%) or type 4 (40.98%),and those thicker than 8 mm regressed to type 1 (35.00%) or type 3 (50.00%). Tumors in the macular area most often to type 3 (45.10%) or type 4 (33.33%),and those in the macular to equator area and the equator to ora serrata region most often to type 4 (54.35%,80.48%). 14 tumors recurred,2 tumors were type 0,3 tumors were type 1,1 tumor was type 2 and 8 tumors were type 3. Conclusions Following chemoreduction,type 4 and type 3 regression patterns were most common. Following chemoreduction,most small retinoblastomas result in a flat scar,intermediate tumors in a flat or partially calcified remnant,and large tumors in a more completely calcified remnant. Tumor recurrence was usually found fol-lowing regression pattern type 3.

关键词

视网膜母细胞瘤/抗肿瘤联合化疗方案/冷冻治疗/肿瘤消退/自行性

Key words

retinoblastoma/antineoplastic combined chemotherapy protocols/cryotherapy neoplasm/regres-sion/spontaneous

引用本文复制引用

田明星,周炼红,叶美红,罗琪,徐永红..视网膜母细胞瘤化疗减容加局部治疗瘤体后的临床消退类型分析[J].中国斜视与小儿眼科杂志,2014,(2):5-8,49,5.

中国斜视与小儿眼科杂志

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1005-328X

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