摘要
Abstract
Objective Through the clinical use of patients with cerebral apoplexy citalopram treatment, observe patients the clinical effects of and in the course of treatment adverse reactions. Methods In this paper, the selected 100 cases of stroke patients with symptoms of depression after concurrent from our hospital from January 2009 to May 2011 months of selection, 100 cases were randomly divided into two groups, and 50 cases. Clinical treatment process and given two groups of patients conventional stroke antiplatelet agents and related cerebrovascular aspects of the drugs. The treatment group in patients with primary stroke disease treatment on the basis of using citalopram, once a day oral, dose of 20 to 40 mg. Patients in the control group primary stroke disease treatment on the basis of using paxil, the initial dose of 20 mg/d, early morning hol ow oral. Through the clinical to patients with cerebral apoplexy using two different clinical observation methods, analyzes patients use citalopram after treatment of depression, and the patients' overal significant efficiency the statistics, use ham-d before and after treatment for patients with 1, 2, 4, 6 weeks observed score. Results Two groups of stroke patients with depression symptoms after clinical treatment carries on the comparison, the treatment group of patients total significant efficiency is 92.0%, and the control group of patients total significant efficiency is 76.0%, two groups of patients' overal significant efficiency compared with statistical differences (P<0.05). And the treatment group stroke patients with clinical symptoms of depression after ease, explain citalopram has the very high treatment effect. Conclusion Citalopram could ameliorate PSD patient’s clinical symptoms with lesser side-effect and make patient’s mentality better and obtain good prognosis.关键词
脑卒中后抑郁/西酞普兰/脑卒中/临床治疗Key words
Post-stroke depression/Citalopram/Stroke/Clinical treatment分类
医药卫生
