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血清Hcy检测在T2DM早期肾损伤中临床应用价值的探讨

杜晓红 郭敏 杨祥松 谈涛

中国药物经济学Issue(1):208-210,3.
中国药物经济学Issue(1):208-210,3.

血清Hcy检测在T2DM早期肾损伤中临床应用价值的探讨

Detection of Serum Hcy in the Clinical Application Value of Renal Injury in Early Stage of T2DM

杜晓红 1郭敏 1杨祥松 1谈涛1

作者信息

  • 1. 松滋市人民医院检验科,湖北荆州 434200
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摘要

Abstract

Objective Study of serum homocysteine detection in the clinical application value of early renal injury in T2DM.Methods 115 cases of T2DM patients, serum homocysteine treated in this hospital in 2009 October~2013 years 6 months, glycosylated hemoglobin, urinary albumin, serum creatinine were detected. According to the mALB DM patients were divided into three groups, 40 healthy people for medical examination in our hospital at the same period as the normal control group, and to compare the results of four groups of detection.Results The content of serum Hcy in patients with T2DM than in healthy controls, with a statistical significant difference between the groups (P<0.05 orP<0.01);serum Hcy content and course of disease, mALB, CREA levels were positively (r were 0.66, 0.59, 0.46),P<0.05.Conclusion With the increase of serum Hcy level in patients with T2DM, Urinary mALB levels gradualy increased. The results suggest that the serum levels of Hcy and urine mALB can dynamicaly view kidney patients T2DM micro vascular lesions, To improve DM and EDN diagnosis, Has good clinical application value.

关键词

同型半胱氨酸/T2DM/糖尿病早期肾损伤

Key words

Homocysteine/T2DM/Early diabetic renal damage

分类

医药卫生

引用本文复制引用

杜晓红,郭敏,杨祥松,谈涛..血清Hcy检测在T2DM早期肾损伤中临床应用价值的探讨[J].中国药物经济学,2014,(1):208-210,3.

中国药物经济学

1673-5846

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