摘要
Abstract
Objective:To analyze and compare the efficacy and safety of Oxaliplatin and Pirarubicin intervention on primary liver cancer.Method:Seventy-six primary liver cancer patients in our hospital from January 2009 to December 2012 were selected as the research objects,and then randomly divided into the study group and the control group,38 cases in each group.The study group was treated with pirarubicin intervention,the control group was treated with interventional therapy.The effect and safety comparison of two groups were analyzed,including the incidence of clinical total effective rate,disease control rate,clinical symptom improvement rate of decline,the rate of tumor markers,time to progression,adverse reaction;Time to progression than patients in the two groups of 12 months were analyzed,and determined the factors that affect on the long-term effect of interventional therapy Result:The total effective rate,average progression free survival and tumor marker decline rate of the treatment group were better than those of the control group,the differences were statistically significant(P<0.05),but the two groups of patients in disease control rate,clinical symptom improvement rate had no significant difference(P>0.05).Through the analysis,factors affecting the long-term effect of interventional treatment, including portal vein involvement,lesions were non enveloped and postoperative combined with anticancer drugs.Conclusion:In patients with primary liver cancer with pirarubicin intervention therapy,is a safe and effective,and can improve the progression free survival,compared with pirarubicin intervention therapy effect is better,it is worth the clinical promotion and application.关键词
奥沙利铂/吡喃阿霉素/介入治疗/原发性肝癌/疗效/安全性Key words
Asha Leigh Per/Pirarubicin/Interventional therapy/Primary liver cancer/Efficacy/Safety
