中国医学创新Issue(36)：13-14,2.DOI:10.3969/j.issn.1674-4985.2013.36.005
二甲双胍和罗格列酮治疗2型糖尿病肾病的效果观察
Observation on Clinical Effect of Melbine Combined with Rosiglitazone on Treating Type 2 Diabetic Mellitus
摘要
Abstract
Objective:To observe the clinical effect of melbine and rosiglitazone on treating type 2 diabetic mellitus. Method:80 patients with type 2 diabetic mellitus were randomly divided into two groups. They were treated by rosiglitazone and melbine respectively. The Urine protein quantitation in 24 hours,microalbuminuria,renal function were compared. Result:The FPG,2 h PG and HbA1c declined obviously,with similar degrees. The UAE, UAER and TG declined too,HDL-C increased(P<0.05). There was no statistically significant in TC and LDL-C(P>0.05). In the treatment group, 12 cases were significantly effective,22 cases effective,6 cases were invalidity,the total effective rate was 85 percent. In the control group,8 cases were significantly effective,18 cases effective,14 cases were invalidity,the total effective rate was 65 percent. Conclusion:It can improve the insulin-resistance,reducing blood sugar levels,and it can significantly reduced urine protein and improve the renal function.关键词
罗格列酮/二甲双胍/2型糖尿病/糖尿病肾病Key words
Rosiglitazone/Melbine/Type 2 diabetic mellitus/Diabetic nephropathy引用本文复制引用
胡碧海..二甲双胍和罗格列酮治疗2型糖尿病肾病的效果观察[J].中国医学创新,2013,(36):13-14,2.基金项目
江西省科技厅课题省级成果 （）
