摘要
Abstract
Objective:To observe the clinical effects of bronchia alveolar wash combined with mechanical ventilation on COPD patients complicated with respiratory failure.Method:Fifty-eight COPD patients complicated with respiratory failure were selected in our hospital from May 2011 to April 2013,they were randomly divided into the control group and the observation group,29 cases in each group.The control group was given conventional symptomatic treatment and invasive/non-invasive sequential mechanical ventilation,and the observation group was given bronchia alveolar lavage on the basis of the control group.PaO2,PaCO2 and pH of two groups were detected before and after treatment,and mechanical ventilation time,length of stay and incidence of complication were recorded.Result:After treatment,PaO2,PaCO2 and pH of two groups both improved and the observation group were better than the control group,the differences had statistically significant(P<0.05).The duration of mechanical ventilation in the treatment group was (12.5±4.5)d,it was significantly less than that in the control group(21.5±6.6)d,hospitalization time(19.7±5.6)d was significantly less than that in the control group(30.8±6.6)d,the incidence of complications was 3.4%,it was significantly lower than the control group of 37.9%,the differences had statistically significant(P<0.05).Conclusion:Bronchia alveolar lavage combined with mechanical ventilation has curative effect,is safe and reliable,and can significantly shorten mechanical ventilation time and reduce the incidence of complication.关键词
慢性阻塞性肺疾病/支气管镜肺泡灌洗/机械通气Key words
COPD/Bronchia Alveolar Lavage/Mechanical Ventilation
