中国医学创新Issue(36)：130-131,132,3.DOI:10.3969/j.issn.1674-4985.2013.36.060
探讨外周血CD4+、CD8+T细胞CD69在小儿类风湿关节炎发生过程中的免疫病理作用
Study on Peripheral Blood CD4+,CD8+T Cells Expression of CD69 in Pediatric Patients with Rheumatoid Arthritis during Immune Pathology
康辉 1邹峥1
作者信息
- 1. 江西省儿童医院 江西 南昌 330006
- 折叠
摘要
Abstract
Objective:To explore the expression and immunopathological effects of CD4+、CD8+T cells in the peripheral blood of CD69 for the cells belong to the children with rheumatoid arthritis(RA)in the process. Method:Thirty cases of rheumatoid arthritis children and 30 cases health children from July 2011 to September 2012 were randomly divided into two groups. The former was the observation group and the other was the control group. Then collecting the peripheral blood samples of two groups of children were used to test of CD4+,and CD8+T cell for CD69 with the method of medical. The effect of drug and the expression level situation of CD4+,and CD8+T cell for CD69 of the observation group were tested after treatment. Result:The expression level of the observation group was significantly higher than the control group(P<0.05). After drug therapy,the children’s RA symptoms improved clearly. Blood testing of re-extract the peripheral found that the level significantly declined than before(P<0.05).Conclusion:CD4+、CD8+T cells in the peripheral blood of CD69 can activate and proliferate the disease. Palliative effect can be achieved through the control of CD4+、CD8+T cells in the peripheral blood of CD69.关键词
外周血/小儿类风湿关节炎症/免疫病理作用Key words
Peripheral blood/Children with rheumatoid joint inflammation/Immune pathological role引用本文复制引用
康辉,邹峥..探讨外周血CD4+、CD8+T细胞CD69在小儿类风湿关节炎发生过程中的免疫病理作用[J].中国医学创新,2013,(36):130-131,132,3.
