中国医学创新Issue(3)：5-8,4.DOI:10.3969/j.issn.1674-4985.2014.03.003
天津市高中生血清谷丙转氨酶升高与高尿酸血症的关系
The Relationship between Alanine Aminotransferase and Hyperuricemia among High School Students in Tianjin
摘要
Abstract
Objective:To explore the association between alanine aminotransferase(ALT) and hyperuricemia. Method:A total of 1895 high school students aged 17 to 21 who attended the regular health examination were investigated. ALT,serum uric acid(SUA),lipid profiles, fastingplasmaglucose(FPG),etc.They were determined by automatic biochemical analysis device. Weight,height and blood pressure were measure with the same instruments. Subjects were grouped according to ALT level or body mass index(BMI) in both gender. Multiple logistic regression analysis was used to analyze the risk factors of elevated ALT level. Result:The ALT-elevated rate was 7.65%(11.63%)in male and 3.54%in female(P<0.01). Compared to normal-ALT group,SUA,BMI,SBP,TG,LDL were significantly increased in ALT-elevated group in both gender(P<0.05). TC,HDL were significantly different in female but not in male(P<0.05). The liner regression showed that the ALT level was positively related to SUA in both gender(P<0.01). Multiple logistic regression analysis showed that hyperuricemia,overweight,abnormal BMI were risk factor of elevated ALT(OR 1.956, 2.559,9.083 in male,2.962,3.456,5.185 in female). And elevated FPG and hypertension had no statistical significance(P>0.05)Conclusion:Hyperuricemia is associated with elevated ALT.关键词
谷丙转氨酶/高尿酸血症Key words
Alanine aminotransferase/Hyperuricemia引用本文复制引用
俞婧,吴皓,李明珍,孙丽荣..天津市高中生血清谷丙转氨酶升高与高尿酸血症的关系[J].中国医学创新,2014,(3):5-8,4.基金项目
国家自然科学基金资助项目 （）
