摘要
Abstract
Objective:To investigate lower respiratory tract infection common pathogens distribution and drug for clinical rational use of antibiotics reference in this region. Method:From January 2011 to December 2012,among hospitalized patients with lower respiratory tract infection sputum culture isolated pathogens were identified with drug analysis. Result:The 1603 qualified specimens,819 live bacteria were isolated,including gram-negative bacteria 609,accounting for 74.36%,Gram-positive cocci 152,accounting for 18.56%,fungi 58,accounting for 7.08%. Five kinds of bacteria were:Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae,Staphylococcus aureus,and Acinetobacter baumannii,pathogens resistant to various antibiotics differences were quite large and present multi-drug resistant. In Escherichia coli and Klebsiella pneumoniae produced ultra broad spectrum in the check b lactamase(ESBLs)strain rate were 51.77%(73/141),40.68%(48/118);Methicillin-resistant staphylococcus aureus(MRSA)detection rate was 41.12%(44/107). Conclusion:Gram-negative bacilli are common. Susceptibility results shows that drug resistant is serious,and ESBL-producing strains of MRSA increase lead to multiple antibiotics,attention should be paid and pathogen detection and monitoring of drug resistance should be enhanced,with rational use of antimicrobial drugs to reduce drug-resistant strains.关键词
下呼吸道感染/病原菌分布/耐药性Key words
Lower respiratory tract infections/Pathogen distribution/Drug resistance