中国医学创新Issue(4)：116-117,2.DOI:10.3969/j.issn.1674-4985.2014.04.051
我院荨麻疹患儿体外过敏原分析
Analysis of In Vitro Allergens in Children with Urticaria
汪叶红 1李德庚 1王克明1
作者信息
- 1. 广东省中山市博爱医院 广东 中山 528403
- 折叠
摘要
Abstract
Objective:To investigate and discuss the situation of allergens in children with urticaria in our hospital. Method:Total serum immunoglobulin(TIgE)was detected by IgE ELISA kit(chemiluminescence). Phadiatop,Fx5E and specific IgE(SIgE)were tested by fully automatic in vitro allergen detection system(ImmunoCAP250,Phadia Company)with fluorescent enzyme-linked immunoassay. Result:In 193 patients with urticaria,99.3%was detected with positive TIgE. The positive rates of Phadiatop and Fx5E were 32.1%and 49.7%separately,and the aggregate of the two rates was 59.8%. Inhalant allergens were mainly consisted of house dust and mites(47.6%)while ingested allergens were primarily composed of milk and eggs(56.3%,52.6%). The positive rate of Fx5E was significantly higher than that of Phadiatop among children 0 to 3 years old(45.2%vs 26.2%, P<0.05),but which in patients aged above 3 years old had no significant difference(P>0.05). Conclusion:Atopic constitution is common in children with urticaria,and approximately 60%cases are related to type I hypersensitivity. Inhalant allergens are mainly composed of house dust and mites,and ingested allergens are mainly composed of milk and eggs. Ingested allergens are the most common reason for urticaria in children 0-3 years old while in children above 3-year,ingested and inhalant allergens are equally important.关键词
荨麻疹/总IgE/吸入物过敏原过筛试验/食物过敏原过筛试验/特异性IgEKey words
Urticaria/TigE/Phadiatop/Fx5E/SIgE引用本文复制引用
汪叶红,李德庚,王克明..我院荨麻疹患儿体外过敏原分析[J].中国医学创新,2014,(4):116-117,2.
