中国医学创新Issue(5)：8-9,2.DOI:10.3969/j.issn.1674-4985.2014.05.004
聚乙二醇化重组人粒细胞刺激因子与重组人粒细胞刺激因子临床疗效比较
Clinical Curative Effect Comparation of Polyethylene Glycol(peg)of Recombinant Human Granulocyte Stimulating Factor and ;Recombinant Human Granulocyte Stimulating Factor
董赟 1吴毓东 1李德俊 1付琴 1程晓丹1
作者信息
- 1. 江西省肿瘤医院 江西 南昌 330029
- 折叠
摘要
Abstract
Objective:To compare the effect of the application of polyethylene glycol(peg)recombinant human granulocyte stimulating factor and recombinant human granulocyte stimulating factor to prevent granulocytopenia after TAC scheme chemotherapy. Method:60 cases of breast cancer treated by TAC scheme chemotherapy from January 2013 to August 2013 hospitalized were randomly divided into two groups. The experimental group was treated with the polyethylene glycol recombinant human granulocyte stimulating factor(PEG-rhG CSF)after the end of the chemotherapy for 48 hours.The control group was treated with recombinant human granulocyte stimulating factor(rhG CSF)after the end of the chemotherapy for 48 hours.Result:The case of neutropenia and infection of experimental group in chemotherapy intermission were obviously less than that of the control group,there was statistical significance(P<0.05).Conclusion:The curative effect of polyethylene glycol(peg)of recombinant human granulocyte stimulating factor injection in preventing breast cancer TAC scheme post-chemotherapy neutropenia is good,and is worth to be widely applied in clinical.关键词
乳腺癌/聚乙二醇化重组人粒细胞刺激因子/粒细胞减少Key words
Breast cancer/Polyethylene glycol(peg)filgrastim/Granulocytopenia引用本文复制引用
董赟,吴毓东,李德俊,付琴,程晓丹..聚乙二醇化重组人粒细胞刺激因子与重组人粒细胞刺激因子临床疗效比较[J].中国医学创新,2014,(5):8-9,2.
