中国医学创新Issue(5)：12-13,14,3.DOI:10.3969/j.issn.1674-4985.2014.05.006
早期检测颅脑损伤患者血清S-100B蛋白含量的临床意义
The Clinical Significance of Detecting S-100B Protein Level in Serum of Craniocerebral Injury Patients at Early Stage
张福成 1赵学明2
作者信息
- 1. 山西医科大学 山西 太原 030001
- 2. 山西煤炭中心医院
- 折叠
摘要
Abstract
Objective:To explore the relationship between S-100B protein and craniocerebral injury severity and prognosis, which provid theoretical basis for diagnosis, prognosis assessment and treatment by detecting S-100B protein level in serum of craniocerebral injury patients. Method:Thirty cases from normal health examination were chose as control group and the serum samples were taken to detect S-100B protein level. Sixty cases with craniocerebral injury were taken serum sample at early stage(2-6 h), 1, 2, 3, 5, 7, 10 days after the injury, the S-100B protein levels in serum in different time were detected and compared. Result:The serum S-100B protein level had significant difference between control group and the craniocerebral injury patients(P<0.05)except the moderate tenth. The GCS>8 group patients, the GCS≤8 group patients, and the different prognosis group patients S-100B protein content were remarkably differences(P<0.05). Conclusion:The S-100B protein, which is a kind of effective biochemical indicator, has high sensibility and specificity in the diagnosis of brain injury and severity, and could provide theoretical basis for diagnosis of brain injury, prognosis evaluation and treatment.关键词
颅脑损伤/S-100B蛋白/预后Key words
Craniocerebral injury/S-100B protein/Prognosis引用本文复制引用
张福成,赵学明..早期检测颅脑损伤患者血清S-100B蛋白含量的临床意义[J].中国医学创新,2014,(5):12-13,14,3.
