中国医学创新Issue(5):105-107,3.DOI:10.3969/j.issn.1674-4985.2014.05.047
高血压病患者血清sLOX-1与hs-CRP的相关性研究
Relationship Research between Serum sLOX-1 and hs-CRP in Patients with Hypertension
董西刚 1孙旭 1孙秀芹 2李欣1
作者信息
- 1. 山东省枣庄市峄城区人民医院 山东 枣庄 277300
- 2. 山东省枣庄市峄城区吴林街道卫生院
- 折叠
摘要
Abstract
Objective:To investigate the level of serum soluble lectin-like oxidized low-density lipoprotein receptor-1(sLOX-1)and high sensitivity C-reactive protein(hs-CRP)in patients with hypertension. Method:Serum sLOX-1 and hs-CRP concentration hs-CRP in 139 patients with hypertension(including 46 cases of low risk group,46 cases of risk group,47 cases of high-risk group)and 48 cases of healthy controls were detected by enzyme-linked immunosorbent assay(ELISA). Result:Serum sLOX-1 and hs-CRP concentration significantly increased as the disease worsens(the control group,the low risk group,the risk group,the high-risk group). Increased levels of serum sLOX-1 concentration were correlated with serum hs-CRP concentration(r=0.346,P=0.000). Conclusion:Serum sLOX-1 and hs-CRP might provid two new ways to diagnose and evaluate hypertension.关键词
可溶性凝集素样氧化型低密度脂蛋白受体-1/超敏C反应蛋白/高血压病/炎症标记物Key words
Soluble lectin-like oxidized low-density lipoprotein receptor-1/High sensitivity C-reactive protein/Hypertension/Biomarker引用本文复制引用
董西刚,孙旭,孙秀芹,李欣..高血压病患者血清sLOX-1与hs-CRP的相关性研究[J].中国医学创新,2014,(5):105-107,3.