中国医学创新Issue(6)：40-41,2.DOI:10.3969/j.issn.1674-4985.2014.06.016
小剂量辛伐他汀对稳定期慢性阻塞性肺疾病患者生活质量的影响
Effect on Small Doses of Simvastatin on Quality of Life of Patients with Chronic Obstructive Pulmonary Disease
摘要
Abstract
Objective:To observe the low-dose simvastatin(10 mg/times,once a night)a period of one year of treatment for moderate stable chronic obstructive pulmonary disease(COPD)patients quality of life impact.Method:60 patients with moderate stable chronic obstructive pulmonary disease were randomly divided into the experimental group and the control group,30 cases in each group.The control group was treated with conventional therapy for one year,the experimental group was treated with oral simvastatin 10 mg/times,once a night for 1 year on the basis of conventional therapy. COPD assessment test(CAT)score of the two groups before and after one year were recorded and compared.Result:Before treatment,the CAT scores had no significant differences between the two groups(P>0.05),after one year of treatment,CAT scores of the two groups were significantly better than before treatment,and CAT of the experimental group was significantly better than the control group,the differences were statistically significant(P<0.05). Conclusion:Low-dose simvastatin can improve the quality of life in patients with COPD,it is worth promoting in clinical practice.关键词
慢性阻塞性肺疾病/辛伐他汀Key words
Chronic obstructive pulmonary disease/Simvastatin引用本文复制引用
余胜忠,赵宇,李元广..小剂量辛伐他汀对稳定期慢性阻塞性肺疾病患者生活质量的影响[J].中国医学创新,2014,(6):40-41,2.基金项目
2012年深圳市宝安区科学技术局立项 （）
