中国医学创新Issue(6)：107-108,109,3.DOI:10.3969/j.issn.1674-4985.2014.06.044
长托宁在老年ERCP麻醉前用药的临床观察
Clinical Observation of Penehyclidine Hdrochloride in Pemedication of ERCP in Ederly Ptients
龚建平 1梁秀生1
作者信息
- 1. 广东省清远市人民医院 广东 清远 511500
- 折叠
摘要
Abstract
Objective:To investigate feasibility,efficacy and safety of penehyclidine hydrochloride used as premedication of ERCP in elderly patients. Method:90 elderly patients undergone ERCP surgery under intravenous anesthesia from May 2009 to February 2013 in our hospital were randomly divided into three groups:penehyclidine hydrochloride group(30 cases),atropine group(30 cases)and physiological saline group(30 cases). Three groups respectively used penehyclidine hydrochloride,atropine and physiological saline as premedication. Changes of SBP,DBP,HR and saliva secretion volume of the three groups at different time points after premedications were compared,at the same time intraoperative and postoperative adverse reactions in three groups were compared. Result:Blood pressures of the three groups changed smoothly,and changes of heart rates of patients in the penehyclidine hydrochloride group was smoother than that of the atropine group,and there was no significant difference when that in the penehyclidine hydrochloride group compared with that in the physiological saline group. Saliva secretion volumes in penehyclidine hydrochloride group were significantly less than that in the atropine group and the physiological saline group. Changes of heart rates of patients in the atropine group before and after dosing had significant difference. Conclusion:Penehyclidine hydrochloride has a small circulating hemodynamic effect in elderly patients when it is used as premedication in geriatric ERCP,and anti-cholinergie effect of penehyclidine hydrochloride is more sustainable than that of atropine,and penehyclidine can effectively control respiratory secretions during the perioperation,and it is a more ideal premedication of elderly patients.关键词
长托宁/老年患者/ERCP/麻醉前用药Key words
Penehyclidine hydrochloride/Elderly patients/ERCP/Premedication引用本文复制引用
龚建平,梁秀生..长托宁在老年ERCP麻醉前用药的临床观察[J].中国医学创新,2014,(6):107-108,109,3.
