中国医学创新Issue(7)：50-52,3.DOI:10.3969/j.issn.1674-4985.2014.07.020
烧伤患者早期合并心肌细胞及心功能损害的临床监测
Clinical Monitoring on Early Combined Damage of Myocardial Cell and Cardiac Function in Burn Patients
安振国 1李召芳 1杨文东1
作者信息
- 1. 山东省利津县第二人民医院 山东 利津 257447
- 折叠
摘要
Abstract
Objective:To explore the clinical value of h-FABP and NT-proBNP in monitoring early combined damages of myocardial cells and cardiac function by observing change of serum h-FABP and NT-proBNP level in early burn patients.Method:A total of 49 cases with myocardial cell damage(the damage group)and 50 healthy people(the control group)were selected as the research objects.Serum h-FABP was detected by ELISA one-step,and serum NT-proBNP was inspected by ECLIA method.Result:The positive rate of serum h-FABP in burn patients(80.3%)before the treatment was significantly higher than that of NT-proBNP(50.8%)(P<0.01).The level of serum NT-proBNP and h-FABP in the damage group before treatment were significantly higher than that in the control group(P<0.01),and that of the two groups after treatment were significantly lower than that before treatment(P<0.01),and that of the two groups after the treatment had no significant difference(P>0.05).Electrocardiogram(ECG)and heart function examination had no abnormal performance. Serum NT-proBNP and h-FABP had significant positive correlation(r=0.629,P<0.01),and the correlation was good. Conclusion:Combined detection levels of serum NT-proBNP and h-FABP can early diagnose damage of myocardial cells and heart function in burn patients and can also be used to observe the clinical curative effects.关键词
烧伤早期/N末端B型钠尿肽原/心脏型脂肪酸结合蛋白/早期诊断Key words
Burn early/NT-proBNP/H-FABP/Early diagnosis引用本文复制引用
安振国,李召芳,杨文东..烧伤患者早期合并心肌细胞及心功能损害的临床监测[J].中国医学创新,2014,(7):50-52,3.
