中国医学创新Issue(9)：131-133,134,4.DOI:10.3969/j.issn.1674-4985.2014.09.052
青蒿素类抗疟药的作用机制及耐药机制研究进展
Research Progress in Antimalarial Mechanism and Drug-resistant Mechanism of Artemisinin and Its ;Derivatives
摘要
Abstract
Artemisinin as an important antimalarial drug,because of its antimalarial action quickly,high efficiency, low toxicity and with most of the advantages of antimalarial drugs without cross resistance,become the main current global antimalarial drugs.Although in the thai-cambodian border region has been the emergence of artemisinin resistance,but at present all over the world use artemisinin-based combination therapy(ACT)curative effect for the treatment of malaria still can reach more than 90%,so just phenomenon of artemisinin resistance must be quickly take containment action.This paper describes the antimalaria mechanism of artemisinin,discuss the mechanism of drug resistance to artemisinin,and development prospect are summarized in this paper.关键词
青蒿素/抗疟药/作用机制/耐药性机制Key words
Artemisinin/Antimalarial/Action mechanism/Resistance mechanism引用本文复制引用
罗丹,刘伟光,杨亚明..青蒿素类抗疟药的作用机制及耐药机制研究进展[J].中国医学创新,2014,(9):131-133,134,4.基金项目
云南省社会发展科技计划项目 （）
