摘要
Abstract
Objective:To compare effects of Propofol and Etomidate combined with Dezocine respectively for sedated gastrointestinal scope in elderly patients. Method:82 elderly patients with ASAⅠ-Ⅲwere scheduled for sedated gastrointestinal scope,were randomly divided into two groups with random number table:Propofol+Dezocine group(P group) and Etomidate+Dezocine group(E group),each group had 41 cases. The MAP,HR and SpO2 were recorded before drug injection(T0),before examination(T1),1 minute after examination(T2),end examination(T3)and consciousness recovery (T4). The incidence of myoclonus,body movements,respiratory depression,nausea,vomit,dizziness and examination time,consciousness recovery time after drug withdrawal were recorded during examination. Result:In the group P,the MAP, SpO2 significantly decreased after drug injection(P<0.05)and rised in T3,T2 in turn. In the group E,the MAP,HR were insignificant difference between each time point(P>0.05)and the SpO2 was significant decreased after drug injection(P<0.05) and rised in T2. In T1 and T2 the MAP was significant lower in group P than that in group E(P<0.05). There was insignificant difference between the two groups in consciousness recovery time after drug withdrawal(P>0.05). Compared with group P,the incidence of myoclonus,nausea,vomit were significant higher than that in group E(P<0.05). Conclusion:Both propofol and etomidate combined with dezocine for sedated gastrointestinal scope is safe and effective in elderly patients,but propofol combined with dezocine has the advantage of slight effects on the cardiovascular system and less adverse reactions.关键词
丙泊酚/依托咪酯/地佐辛/胃肠道内窥镜/镇静Key words
Propofol/Etomidate/Dezocine/Gastrointestinal scope/Sedation
