摘要
Abstract
Objective:To investigate the clinical determination significance of serum N terminal B type pro-B-type natriuretic peptide in the treatment of ACS.Method:153 cases of ACS patients with ICU in our hospital were selected,the serum NT-pro BNP level,Gensini coronary artery score and left ventricular ejection fraction(LVEF)were detected and evaluated,and were compared with 93 healthy subjects(control group)and 86 patients with stable angina pectoris(SAP group).At the same time,the serum NT-pro BNP level changes of the 153 patients with ACS before and after treatment in 7,15 days after were compered. Result:⑴Compared with the control group and SAP group,with NT-pro BNP levels, Gensini coronary artery score in the ACS patients were significantly increased,LVEF was decreased(P<0.05).And the SAP group,UAP group,AMI group,Gensini NT-pro BNP score was gradually increased,LVEF was gradually decreased (P<0.05).⑵In 153 ACS patients ,after the treatment,80 cases were discharged,34 cases were worsening heart failure, 39 cases were died.The serum NT ProBNP in discharged patients group was significantly decreased after 7 d treatment (P<0.05),and it was gradually reduced after 7,15 days.And serum NT ProBNP was gradually increasing trend in death group and heart failure group patients(P<0.05). Conclusion:Serum NT-pro BNP is evaluation of clinical diagnosis and heart function in favor of ACS,can be used as an important index to evaluate the treatment outcome of ACS monitoring.关键词
心功能/NT-pro BNP/诊断/预后评估Key words
Cardiac function/NT-pro BNP/Diagnosis/Prognosis
