中国医学创新Issue(12):151-153,154,4.DOI:10.3969/j.issn.1674-4985.2014.12.058
肺炎克雷伯菌耐药机制的研究进展
Research Progress on the Resistant Mechanism for Klebsiella Pneumoniae
摘要
Abstract
Klebsiella pneumoniae is an important opportunistic pathogen and iatrogenic infection of bacterium,the main mechanism of drug resistance are producing antibiotic drug inactivation of enzyme,antimicrobial drug permeation barriers(the biofilm and outer membrane protein deficiency),changing the drug target,hyperthyroidism role of active efflux pump system,the integron,and so on.It plays a crucial role in the control the spread of resistant organism and more rational use of antibiotic to understand the mechanism of drug resistance for Klebsiella pneumoniae.In this review,the current research progress on the mechanisms of drug resistance are described.关键词
肺炎克雷伯菌/耐药机制/β-内酰胺酶/整合子Key words
Klebsiella pneumoniae/Resistant Mechanism/Beta-lactamase/Integron引用本文复制引用
林华胜,张薇,李国明..肺炎克雷伯菌耐药机制的研究进展[J].中国医学创新,2014,(12):151-153,154,4.基金项目
广东省自然科学基金项目 ()