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肺炎克雷伯菌耐药机制的研究进展

林华胜 张薇 李国明

中国医学创新Issue(12):151-153,154,4.
中国医学创新Issue(12):151-153,154,4.DOI:10.3969/j.issn.1674-4985.2014.12.058

肺炎克雷伯菌耐药机制的研究进展

Research Progress on the Resistant Mechanism for Klebsiella Pneumoniae

林华胜 1张薇 1李国明1

作者信息

  • 1. 广东医学院 广东 东莞 523808
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摘要

Abstract

Klebsiella pneumoniae is an important opportunistic pathogen and iatrogenic infection of bacterium,the main mechanism of drug resistance are producing antibiotic drug inactivation of enzyme,antimicrobial drug permeation barriers(the biofilm and outer membrane protein deficiency),changing the drug target,hyperthyroidism role of active efflux pump system,the integron,and so on.It plays a crucial role in the control the spread of resistant organism and more rational use of antibiotic to understand the mechanism of drug resistance for Klebsiella pneumoniae.In this review,the current research progress on the mechanisms of drug resistance are described.

关键词

肺炎克雷伯菌/耐药机制/β-内酰胺酶/整合子

Key words

Klebsiella pneumoniae/Resistant Mechanism/Beta-lactamase/Integron

引用本文复制引用

林华胜,张薇,李国明..肺炎克雷伯菌耐药机制的研究进展[J].中国医学创新,2014,(12):151-153,154,4.

基金项目

广东省自然科学基金项目 ()

中国医学创新

1674-4985

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