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TCD监测微栓子与急性脑梗死OCSP分型的关系及临床价值探讨

申丽红 梁小乐 高旭光

中国医学前沿杂志(电子版)Issue(10):34-36,3.
中国医学前沿杂志(电子版)Issue(10):34-36,3.

TCD监测微栓子与急性脑梗死OCSP分型的关系及临床价值探讨

The relationship of TCD monitoring of microembolus and acute cerebral infarction OCSP classiifcation and its clinical value

申丽红 1梁小乐 1高旭光2

作者信息

  • 1. 山西省长治市第二人民医院 神经内科,长治 046000
  • 2. 北京大学人民医院 神经内科,北京 100044
  • 折叠

摘要

Abstract

Objective To investigate the relationship of OCSP classiifcation in patients with acute cerebral infarction (ACI) and microembolus (MES) monitoring and the application value of the latter. Methods ACI OCSP classiifcation and TCD-MES monitoring in 134 cases of patients were analyzed. 26 MES-positive patients were randomly divided into two groups: 12 cases in dual anti-platelet drugs therapy group (dual antiplatelets group ) , aspirin enteric-coated tablets 100 mg+clopidogrel bisulfate 75 mg, once daily orally;14 cases in single antiplatelet therapy group (single antiplatelet group ), aspirin enteric-coated tablets 100 mg, once daily orally. All were treated for seven days, observing changes in the number of MES before and after treatment. Results Patients with ACI subtypes:MES positive rate is 42.1%(16/38) in total anterior circulation infarct (TACI)+partial anterior circulation infarct (PACI) groups , higher than lacunar infarction (LACI) group and posterior circulation infarction (POCI) group. The difference between LACI and POCI was not statistically signiifcant (P>0.05). After 7 days treatment, the number of MES was signiifcantly reduced in two groups, but signiifcantly less in the dual antiplatelets group, the difference was signiifcant (P<0.05). Conclusion There is close relationship between MES formation and TACI, PACI. Good application value has been found in TCD-MES monitoring for predicting cerebral ischemic event in high risk populations and evaluating the efifcacy of antiplatelet drugs .

关键词

急性脑梗死/OCSP分型/微栓子/经颅多普勒超声

Key words

Acute cerebral infarction/OCSP classiifcation/Microembolus/Transcranial Doppler ultrasound

引用本文复制引用

申丽红,梁小乐,高旭光..TCD监测微栓子与急性脑梗死OCSP分型的关系及临床价值探讨[J].中国医学前沿杂志(电子版),2013,(10):34-36,3.

基金项目

山西省科技攻关项目 ()

中国医学前沿杂志(电子版)

OACSTPCD

1674-7372

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