中国医学前沿杂志（电子版）Issue(2)：34-37,4.
伴t（1;19）/TCF3-PBX1的儿童急性淋巴细胞白血病的临床研究
A clinical study of TCF3-PBX1 positive in Children with acute lymphoblastic leukemia
摘要
Abstract
Objective To explore clinical and biological features of TCF3-PBX1 fusion gene positive in Children with acute lymphoblastic leukemia acute lymphoblastic leukemia (ALL). Methods We analysed cell morphology, routine blood test results, TCF3-PBXl fusion gene and clinical features in the 17 cases. Results The incidence of 17 TCR3-PBX1-positive children’s ALL was 5.57%of the total. ALL patients of them, 8 male cases, 9 female cases. The median age was 6.4 (1~13) years old. Complete remission rate was 100%;6 cases of balanced translocation. Unbalanced translocation 9 cases. No signiifcant difference between the two groups. Conclusion TCF3-PBX1-positive children’s ALL had unique clinical and pathological features with high remissiion rate.关键词
TCF3-PBXl融合基因/儿童/急性淋巴细胞白血病Key words
TCF3-PBXl fusion gene/Child/Acute lymphoblastic leukemia引用本文复制引用
赖长城,傅睿,李艳红,梁昌达..伴t（1;19）/TCF3-PBX1的儿童急性淋巴细胞白血病的临床研究[J].中国医学前沿杂志（电子版）,2014,(2):34-37,4.基金项目
江西省卫生厅科技计划 （）
