摘要
Abstract
Objective To study the effect of pediatric primary nephrotic syndrome hormone therapy on lymphocytes induced. Methods The diagnosis and treatment of the pediatric department of our hospital from 2012 June to 2013 June in primary nephrotic syndrome and is hormonal treatment in 50 cases as case group, at the same time, the selection of the institute of child health examination in 40 cases as control group (placebo control), lfow cytometry measurements were compared between the two groups of cell lines examined results. Results Cases in treatment group and control group before the lymphoid cell line comparison shows that the parts of CD3+and CD3+, CD4+, CD4+CD25+and NK cells were decreased compared with control group differences were statistically signiifcant (P<0.05), the CD3+CD8+, B cells are elevated compared with control group, difference has statistical signiifcance (P < 0.05);after treatment the levels are changes to the normal values, compared with the control group after treatment of CD3+, CD4+and the content of B cells in the difference between the two groups have statistical signiifcance (P<0.05). Conclusion Hormone treatment children with primary nephrotic syndrome of lymphoid cell lines have influence, plays a certain therapeutic effect.关键词
小儿原发性肾病综合征/激素治疗/淋巴细胞/影响分析Key words
Children with primary nephrotic syndrome/Hormone therapy/Lymphocytes/The impact analysis