中国医学前沿杂志（电子版）Issue(3)：39-42,4.
急性脑梗死患者血清IL-6、IL-8、CRP水平变化及临床意义
Changes and clinical significance of serum interleukin -6, interleukin -8 and C reactive protein in patients with acute cerebral infarction
摘要
Abstract
Objective To investigate the changes and clinical significance of serum interleukin-6 (IL-6), interleukin-8 (IL-8) and C reactive protein (CRP) in patients with acute cerebral infarction (ACI). Methods According to the degree of nervous function defect, 60 cases of cerebral infarction patients were divided into 3 groups:18 cases of light-type group (4~15 score), 30 cases of medium-type group (16~30 score) and 12 cases of gravis-type group (31~45 score);Serum levels of IL-6, IL-8 and CRP in ACI patients were detected by solid-phase enzyme-linked immunosorbent assay (ELISA) at 1d, 7d and 14d after attacked. 30 normal healthy peoples were set as control group. Results Compared with control group, serum levels of IL-6, IL-8 and CRP in ACI group increased signiifcantly (P<0.05 or P<0.01) and reached the peak at 7d after attacked. Compared with light-type group and medium-type group, the serum levels of IL-6, IL-8 and CRP in gravis-type group increased obviously (P<0.05 or P<0.01). Three indicators in light-type group were lower than those in medium-type group (P<0.05). Conclusion IL-6, IL-8 and CRP may participate in the pathogenesis of ACI, and they may be used as new indicators to evaluate the severity and prognosis of ACI.关键词
急性脑梗死/白介素-6/白介素-8/C反应蛋白Key words
Acute cerebral infarction/Interleukin-6/Interleukin-8/C reactive protein引用本文复制引用
秦德友,康俊玲,程超,周丽英,俸军林,曾爱源..急性脑梗死患者血清IL-6、IL-8、CRP水平变化及临床意义[J].中国医学前沿杂志（电子版）,2014,(3):39-42,4.基金项目
广西科学研究与技术开发计划项目（桂科攻10124001B-16）；广西壮族自治区中医药管理局自筹经费科研课题 （）
