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髓过氧化物酶便携式检测系统的硬件设计与研究

莫利明 虞成 杨攀 王清波 马霄

中国医学装备Issue(11):17-20,4.
中国医学装备Issue(11):17-20,4.DOI:10.3969/J.ISSN.1672-8270.2013.11.006

髓过氧化物酶便携式检测系统的硬件设计与研究

Hardware design and research of a portable system for MPO detection

莫利明 1虞成 1杨攀 1王清波 1马霄1

作者信息

  • 1. 杭州市第一人民医院设备科 浙江 杭州 310006
  • 折叠

摘要

Abstract

Objective:Myeloperoxidase (MPO) is an important sort of heme peroxidase. It can be used to identify those patients who will suffer cardiovascular diseases at higher risk in the future. In this paper, we develop a portable system for the determination of MPO by using several electrochemical principles, such cyclic voltammetry, which could gain specific current responses under specific voltages. Methods:A 16-bit, ultra-low-power MCU is utilized in our system to achieve system controlling, the hardware consists of three-electrode detection module, differential amplification module, programmable amplification module and voltage-uplift module. Results:The software is designed to sample the output of hardware, and then processes the data to calculate the concentration of MPO by specific algorithms;the result will be displayed on the LCD screen. Conclusion:The portable system can be used to detect the concentration of MPO in the buffer and in human serum. Thus, the system can be used as a portable platform for MPO detection.

关键词

急性冠脉综合征/髓过氧化物酶/三电极体系/微弱信号放大/便携式

Key words

Acute coronary syndrome/Myeloperoxidase/Three-electrode system/Weak signal amplification/Portable

分类

医药卫生

引用本文复制引用

莫利明,虞成,杨攀,王清波,马霄..髓过氧化物酶便携式检测系统的硬件设计与研究[J].中国医学装备,2013,(11):17-20,4.

基金项目

浙江省科研项目基金(2011C37027)“基于双纳米生物传感器技术的MPO即时检测系统” (2011C37027)

中国医学装备

OACSTPCD

1672-8270

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