中国医学装备Issue(12)：4-7,8,5.DOI:10.3969/J.ISSN.1672-8270.2013.12.002
单探头法和双探头Gates法测定肾小球滤过率的比较研究
Comparative study on the determinations of glomerular filtration rate by Gates method using single and double detector
摘要
Abstract
Objective:Glomerular filtration rate(GFR) is determined by the geometric mean method based on Gates method using dual detector with body thickness instead of kidney depth estimation for using single detector, which can eliminate the error of kidney depth estimation theoretically. The feasibility and accuracy of the geometric mean method were investigated by experiments in this study. Methods: Seventy six cases Community Health residents were selected as the research object. The GFRs(GFRdt, GFRPOST and GFRGM) were determined with two-sample method, Gates method using the post single detector and geometric mean method using double detectors respectively. The accuracy of GFRPOST and GFRGM was analysed and compared using GFRdt as the reference. Results:①Paired t test showed no significant differences between GFRPOST, GFRGM and GFRdt. ②Both GFRdt and GFRPOST changed with GFRdt in linear trend. The correlation coefficients were 0.802 and 0.722 for GFRdt and GFRPOST.③The differences between GFRPOST, GFRGM and GFRdt were-0.5±12.0, 3.0±13.9. Conclusion:The accuracy of the geometric mean method using double detectors is poorer than that of Gates method using the post single detector, which fails to eliminate the error of kidney depth estimation.关键词
肾小球滤过率/双血浆法/肾脏深度/几何均数/放射性核素显像法Key words
Glomerular filtration rate/Dual plasma sample method/Kidney depth/Geometric mean/Radionuclide imaging method分类
医药卫生引用本文复制引用
邵明哲,麻广宇,陈英茂,徐白萱,田嘉禾,陈云爽,孙雪峰..单探头法和双探头Gates法测定肾小球滤过率的比较研究[J].中国医学装备,2013,(12):4-7,8,5.基金项目
国家重点基础研究发展计划(973计划)(2013CB530800)“内脏器官衰老与相关老年疾病防治的基础研究” （973计划）
