中国医药科学Issue(17)：22-24,3.
急性心肌梗死患者急诊PCI术后hs-CRP和NT-proBNP的临床意义及其预测
ClinicalsignificanceandpredictivevalueofhighsensitivityC-reactive proteinandN-terminalpro-brainnatriureticpeptideinpatientswith acute myocardial infarction after primary percutaneous coronary intervention
摘要
Abstract
Objective To investigate the clinical significance and predictive value of high- sensitivity C- reactive protein ( hs-CRP) and N-terminal pro-brain natriuretic peptide in patients with acute myocardial infarction after primary percutaneous coronary intervention (PCI). Methods A total of 80 AMI patients successfully underwent primary PCI and in whom plasma hs-CRP and NT-proBNP were measured,respectively, 24 h,72 h,7 days,30 days and 3 months after PCI.Major adverse cardiac events ( MACE) were observed during hospitalization and within 3-6 months after PCI.Plasma hs-CRP and NT-proBNP levels as well as incidence of MACE in 76 AMI in medically treated group and 30 healthy controls were also examined during the same period and compared with those in PCI group. Results Short-term plasma NT-proBNP levels in medically treated group were significantly higher than those in PCI group,but plasma hs-CRP levels within 72 h-7 days were significantly higher in PCI group compared with those in medicine treatment group.MACE in PCI group was lower than that in medically treated group. Conclusion Both plasma hs-CRP and NT- proBNP are good predictors for mortality and MACE incidence in AMI patients treated with PCI or medications.hs-CRP is a short-term prognostic factor for AMI patients treated with primary PCI,whereas NT-proBNP is a long-term prognostic factor for AMI patients.关键词
急性心肌梗死/高敏C反应蛋白/利钠肽/冠状动脉介入Key words
Acute myocardial infarction/High sensitivity C-reactive protein/N-terminal pro-brain natriuretic peptide/Percutaneous coronary intervention分类
医药卫生引用本文复制引用
刘永,齐国先,孙奡燕..急性心肌梗死患者急诊PCI术后hs-CRP和NT-proBNP的临床意义及其预测[J].中国医药科学,2013,(17):22-24,3.基金项目
沈阳医学院科技基金项目（20137065）。 （）
