中国医药科学Issue(19)：91-92,120,3.
米氮平与舍曲林治疗抑郁症伴有焦虑的临床对比观察
Clinical comparative observation of mirtazapine and sertraline in the treatment of depression with anxiety
戎伟 1李江波 1万承龙 1朱翠珍 1夏晓慧 1桂瑰 1何思忠2
作者信息
- 1. 安徽省芜湖市第二人民医院临床心理科，安徽芜湖241000
- 2. 安徽省芜湖市卫生局，安徽芜湖241000
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy and safety of mirtazapine and sertraline in the treatment of patients of depression with anxiety. Methods 96 patients of depression with anxiety in our hospital were divided into two groups according to different treatment method, each group had 48 cases.The control group were received sertraline treatment, while the observation group were received mirtazapine treatment.The therapeutic effect of two groups were observed. Results There was no significant difference in antidepressant treatment effect between two groups(P>0.05). The anxiolytic treatment effect of the observation group was better than that of the control group,and the difference was statistically significant(P < 0.05). The decreased level of Hamilton Anxiety Scale score and Depression Scale score after a week of treatment in the observation group were better than those in the control group,and the difference was statistically significant(P < 0.05).There was no significant difference in incidence of adverse reactions between two groups(P>0.05). Conclusion The effect of mirtazapine in the treatment of depressive is equivalent to sertraline,but its anxiolytic effect is better than that of the control group,and it has more rapid onset,tolerated adverse reactions,and is worthy of clinical promotion and application.关键词
米氮平/舍曲林/抑郁症/焦虑Key words
Mirtazapine/Sertraline/Depression/Anxiety分类
医药卫生引用本文复制引用
戎伟,李江波,万承龙,朱翠珍,夏晓慧,桂瑰,何思忠..米氮平与舍曲林治疗抑郁症伴有焦虑的临床对比观察[J].中国医药科学,2013,(19):91-92,120,3.
