中国医药科学Issue(19):123-124,139,3.
E-cadherin、Ki-67在乳腺髓样癌中表达及临床病理意义研究
Studies of expression of E-cadherin and Ki-67 protein and clinical pathological significance in the medullary carcinoma of breast
夏云 1瞿伟 1陶珊珊 1涂剑宏1
作者信息
- 1. 南昌市第三医院病理科,江西南昌330009
- 折叠
摘要
Abstract
Objective To explore expression of E-cadherin and Ki-67 protein and clinical Pathological significance in the Medullary Carcinoma of Breast. Methods Using immunohistochemical method to detect the expression of E-cadherin and Ki-67in 42 cases of mammary medullary carcinoma. Results E-cadherin and Ki-67 protein expression positive rate in the medullary carcinoma of breast was 81%(34/42) and 76.2%(32/42).E-cadherin expression positive rate was significantly correlated with lymph node metastases(P < 0.05), and regardless of with age of the patient, tumor size, distant metastasis(P > 0.05).Ki-67 expression rate and positive degree increased with pathology histology classification,lymph node metastasis. Conclusion E-adherin and Ki-67 protein expression difference is the important reasons influence breast medullary carcinoma prognosis.关键词
乳腺髓样癌/E-cadherin/Ki-67/临床病理特征Key words
Medullary carcinoma of breast/E-cadherin/Ki-67/Clinical pathological features分类
医药卫生引用本文复制引用
夏云,瞿伟,陶珊珊,涂剑宏..E-cadherin、Ki-67在乳腺髓样癌中表达及临床病理意义研究[J].中国医药科学,2013,(19):123-124,139,3.