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E-cadherin、Ki-67在乳腺髓样癌中表达及临床病理意义研究

夏云 瞿伟 陶珊珊 涂剑宏

中国医药科学Issue(19):123-124,139,3.
中国医药科学Issue(19):123-124,139,3.

E-cadherin、Ki-67在乳腺髓样癌中表达及临床病理意义研究

Studies of expression of E-cadherin and Ki-67 protein and clinical pathological significance in the medullary carcinoma of breast

夏云 1瞿伟 1陶珊珊 1涂剑宏1

作者信息

  • 1. 南昌市第三医院病理科,江西南昌330009
  • 折叠

摘要

Abstract

Objective To explore expression of E-cadherin and Ki-67 protein and clinical Pathological significance in the Medullary Carcinoma of Breast. Methods Using immunohistochemical method to detect the expression of E-cadherin and Ki-67in 42 cases of mammary medullary carcinoma. Results E-cadherin and Ki-67 protein expression positive rate in the medullary carcinoma of breast was 81%(34/42) and 76.2%(32/42).E-cadherin expression positive rate was significantly correlated with lymph node metastases(P < 0.05), and regardless of with age of the patient, tumor size, distant metastasis(P > 0.05).Ki-67 expression rate and positive degree increased with pathology histology classification,lymph node metastasis. Conclusion E-adherin and Ki-67 protein expression difference is the important reasons influence breast medullary carcinoma prognosis.

关键词

乳腺髓样癌/E-cadherin/Ki-67/临床病理特征

Key words

Medullary carcinoma of breast/E-cadherin/Ki-67/Clinical pathological features

分类

医药卫生

引用本文复制引用

夏云,瞿伟,陶珊珊,涂剑宏..E-cadherin、Ki-67在乳腺髓样癌中表达及临床病理意义研究[J].中国医药科学,2013,(19):123-124,139,3.

中国医药科学

2095-0616

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