中国医药科学Issue(21)：79-80,108,3.
含铂两药联合化疗对老年晚期非小细胞肺癌的临床分析
Clinical analysis of platinum-based doublet chemotherapy for elderly patients with advanced non-small cell lung cancer
张淑立 1王毅 1刘学东 1葛云洁1
作者信息
- 1. 青岛市市立医院呼吸科，山东青岛266011
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of platinum-based doublet chemotherapy for aged patients with advanced non-small cell lung cancer. Methods 60 aged patients(age>70) with advanced non-small cell lung cancer were retrospectively analyzed. As for squamous lung cancer, the first-line treatment was gemcitabine plus cisplatin, and for nonsquamous lung cancer was pemetrexed plus cisplatin, ervery 3 weeks. Results The efficacy and side effects were evaluated for all 60 patients. There were 0 case of CR, 20 cases of PR, 28 cases of SD and 12 cases of PD. The effective rate was 33.3%, disease control rate was 80%, progression free survival was 7.3 months, and main side effects included anergy, leucopenia, anemia, thrombopenia and emesis, without deaths. Conclusion The efficacy and safety of platinum-based doublet chemotherapy for aged patients with advanced non-small cell lung cancer were good and reliable, without unacceptable side effects.关键词
含铂两药/联合化疗/老年人/非小细胞肺癌Key words
Platinum-based doublet/Combination chemotherapy/Aged people/Non-small cell lung cancer分类
医药卫生引用本文复制引用
张淑立,王毅,刘学东,葛云洁..含铂两药联合化疗对老年晚期非小细胞肺癌的临床分析[J].中国医药科学,2013,(21):79-80,108,3.
